Research Article

miR-135a Regulates Atrial Fibrillation by Targeting Smad3

Figure 4

Smad3 and TRPM7 were upregulated in AF and showed a negative correlation with miR-135a. The expression of miR-135a and mRNA levels of Smad3 and TRPM7 in AFs induced by HES (a) and hypoxia (b); Relative protein levels of Smad3 and TRPM7 in AFs treated with HES (c) and hypoxia (d). The levels of proteins were relative to GAPDH expression. (, ).
(a)
(b)
(c)
(d)