Role of K⁺ and Ca²⁺ Channels in the Vasodilator Effects of Plectranthus barbatus (Brazilian Boldo) in Hypertensive Rats

Figure 2

Endothelium-dependent relaxation of hydroethanolic extract of P. barbatus (HEPB) on aortic rings of SHR. Cumulative concentrations of HEPB were added to the Phe-contracted aortic rings. E+ and E- indicate endothelium-intact and endothelium-denuded preparations, respectively (a). Effect of HEPB in the presence of L-NAME (b), ODQ (c), Indo (d), Atro (e), and Prop (f). when compared to the vehicle group and ^# when compared to the HEPB group.

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