Research Article
DUSP22 Ameliorates Endothelial-to-Mesenchymal Transition in HUVECs through Smad2/3 and MAPK Signaling Pathways
Figure 2
DUSP22 downregulation in HUVECs aggravates EndMT. (a) sh-DUSP22 reduced expression of DUSP22 in HUVECs; (b) the cell activity after transfecting the sh-NC and sh-DUSP22; the (c) protein representative blots and (d) quantitative results and the (e) mRNA expression changes of the phenotypic molecule of EndMT after transfecting the sh-NC and sh-DUSP22; the (f) cell migration and (g) invasion changes after transfecting the sh-NC and sh-DUSP22. vs. sh-NC. # vs. sh-NC+TGF-β.
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