Inclusion of Neuropsychological Scores in Atrophy Models Improves Diagnostic Classification of Alzheimer’s Disease and Mild Cognitive Impairment

Table 2

Significant features.

Rank	CN versus AD	P value	Rank	CN versus EMCI	P value
1	Left hippocampus volume	<0.001	1	Age	<0.01
2	Right lateral ventricle volume	<0.001	2	Right inferior temporal volume	<0.01
3	MMSE	<0.001	3	Left thalamus volume	<0.05
4	Right pars opercularis volume	<0.01	4	Right transverse temporal volume	<0.05
5	Age	<0.01	5	Right precuneus volume	<0.05
6	Education	<0.01
7	Fourth ventricle volume	<0.05
8	Left choroid plexus volume	<0.05
9	Right precentral volume	<0.05
10	Whole brain volume	<0.05
Rank	CN versus LMCI	P value	Rank	EMCI versus LMCI	P value
1	Right hippocampus volume	<0.001	1	RAVLT	<0.001
2	Left superior parietal volume	<0.001	2	Right precuneus volume	<0.001
3	MMSE	<0.001	3	Left caudal anterior cingulate volume	<0.001
4	Age	<0.001	4	Left pallidum volume	<0.001
5	Left caudal anterior cingulate volume	<0.01	5	Left cuneus volume	<0.01
6	Left pericalcarine volume	<0.01	6	Left middle temporal volume	<0.01
7	Right superior parietal volume	<0.01	7	Left fusiform volume	<0.01
8	Left amygdala volume	<0.01	8	Left caudal middle frontal volume	<0.05
9	Right lateral occipital volume	<0.05	9	Right precentral volume	<0.05
10	Left caudate volume	<0.05	10	Left thalamus volume	<0.05
11	Left transverse temporal volume	<0.05
12	Left posterior cingulate volume	<0.05
13	Education	<0.05
14	RAVLT	<0.05
Rank	EMCI versus AD	P value	Rank	LMCI versus AD	P value
1	MMSE	<0.001	1	Age	<0.001
2	Left hippocampus volume	<0.001	2	MMSE	<0.001
3	Right lateral ventricle volume	<0.001	3	Non-WM hypointensities Volume	<0.01
4	Right inferior temporal volume	<0.001	4	Right pars triangularis volume	<0.05
5	Right choroid plexus volume	<0.001	5	Left cuneus volume	<0.05
6	Right precentral volume	<0.001
7	Right paracentral volume	<0.01
8	Left caudate volume	<0.05