Inclusion of Neuropsychological Scores in Atrophy Models Improves Diagnostic Classification of Alzheimer’s Disease and Mild Cognitive Impairment
Table 4
Accuracy obtained for each classification pair for neuropsychological, MRI, and Combined Model.
Classification
Neuropsychological model
MRI measures model
Combined model
% Improvement offered by combined model over
Neuropsychological model
MRI measures model
CN versus AD
0.922
0.842
0.939
1.844
11.520
CN versus EMCI
0.846
0.616
0.856
1.182
38.961
CN versus LMCI
0.885
0.714
0.908
2.599
27.171
EMCI versus LMCI
0.634
0.688
0.706
11.356
2.616
EMCI versus AD
0.932
0.814
0.945
1.395
16.093
LMCI versus AD
0.898
0.596
0.901
0.334
51.174
Average
0.853
0.712
0.876
3.118
24.589
% Improvement offered by combined model is calculated as (Combined Model/Neuropsychological Model)/Combined Model 100. % Improvement offered by combined model is calculated as (Combined Model/MRI Model)/Combined Model 1.
