RNA-Seq-Based Breast Cancer Subtypes Classification Using Machine Learning Approaches

Table 5

Top 10 enriched GO terms for Basal-like subtype of BRCA, where the “.adjust” means the values are adjusted by the BH approach.

Basal-like	Top 10 enriched GO terms	adjust
Control group	Morphogenesis of an epithelium	0
	Response to lipopolysaccharide	0
	Response to molecule of bacterial origin	0
	Positive regulation of cell adhesion	0
	Regulation of cell-cell adhesion	0
	Gliogenesis	0
	Peptidyl-tyrosine phosphorylation	0
	Peptidyl-tyrosine modification	0
	Wnt signaling pathway	0
Experiment group	Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	0
	Phospholipase C-activating G protein-coupled receptor signaling pathway	2.18E − 09
	Protein-DNA complex subunit organization	1.33E − 08
	Regulation of cellular response to growth factor stimulus	4.06E − 08
	RNA catabolic process	1.33E − 07
	Regulation of gene silencing by miRNA	1.81E − 07
	Skeletal system morphogenesis	8.43E − 07
	Regulation of gene silencing	9.87E − 07
	Regulation of interferon-gamma production	1.21E − 06
Common	Extracellular structure organization	0
	Lymphocyte differentiation	0
	Regulation of inflammatory response	2.99E − 12
	I-kappaB kinase/NF-kappaB signaling	6.03E − 12
	T cell activation	1.03E − 11
	B cell activation	7.85E − 11
	Positive regulation of response to external stimulus	6.35E − 10
	Ribonucleoprotein complex biogenesis	1.33E − 08
	Formation of primary germ layer	1.29E − 07