The Role of Medication Data to Enhance the Prediction of Alzheimer’s Progression Using Machine Learning

Table 4

The performance for the AD vs sMCI task.

		Testing performance				Cross-validation performance
Model	Dataset	A		R	F1	A		R	F1
RF	CS	94.14	94.14	94.24	94.14	94.76  2.7	94.66  2.9	95.1  2.65	94.71  2.8
	AM	77.48	77.43	77.76	77.48	77.12  4.9	76.8  5.11	78.59  4.8	77.46  5.1
	AM-CS	94.82	94.82	94.83	94.82	94.96  2.4	94.96  2.5	95.20  2.3	94.91  2.4
DT	CS	88.52	88.50	88.66	88.52	93.02  2.7	93.01  2.7	93.36  2.5	93.08  2.7
	AM	73.42	73.22	74.18	73.42	75.76  5.1	75.18  5.2	78.42  5.4	75.76  5.1
	AM-CS	84.91	84.90	85.05	84.91	93.66  3.0	93.76  2.8	93.83  2.7	93.69  2.9
LR	CS	92.34	92.34	92.40	92.34	94.05  2.4	94.5  2.39	94.64  2.3	94.05  2.4
	AM	72.30	71.92	73.54	72.30	78.99  4.2	78.8  4.32	80.02  4.1	78.99  4.2
	AM-CS	95.95	95.95	95.98	95.95	94.12  2.8	94.11  2.8	94.27  2.7	94.12  2.8
SVM	CS	89.86	89.86	89.89	89.86	94.19  3.3	94.18  3.3	94.36  3.2	94.19  3.3
	AM	75.23	75.22	75.24	75.23	77.82  5.9	77.44  6.1	79.5  5.77	77.82  5.9
	AM-CS	90.09	90.09	90.14	90.09	94.50  2.6	94.5  2.61	94.64  2.5	94.5  2.6
KNN	CS	92.79	92.79	92.81	92.79	94.17  2.9	94.16  2.9	94.29  2.9	94.17  2.9
	AM	70.27	70.04	70.94	70.27	78.10  4.0	77.82  4.1	79.46  3.8	78.10  4.0
	AM-CS	94.82	94.82	94.94	94.82	94.00  2.8	93.99  2.8	94.14  2.8	94.0  2.86