[Retracted] NOD1 and NOD2 Are Potential Therapeutic Targets for Cancer Immunotherapy

Figure 2

Structure of bacterial peptidoglycan (PGN) in Gram-positive and Gram-negative bacteria. As a NOD1 selective agonist, ie-DAP is made up of D-γ-Glu and mDAP, which is derived mostly from Gram-negative bacteria. While MDP, as a natural NOD2 agonist, is derived from both Gram-positive and Gram-negative bacteria with a structure composed of MurNAc, L-Ala, and D-γ-Glu.