Role and Mechanism of Keap1/Nrf2 Signaling Pathway in the Regulation of Autophagy in Alleviating Pulmonary Fibrosis

Figure 5

Autophagy affects cell proliferation and apoptosis through KEAP1/Nrf2 signaling pathway. (a) The expression levels of KEAP1 by RT-qPCR. vs. PFC group. vs. PFC + BLM group. (b) The expression levels of Nrf2 by RT-qPCR. vs. PFC group. vs. PFC + BLM group. (c) The expression levels of KEAP1 and Nrf2 by Western blotting assay. vs. PFC group. vs. PFC + BLM group. (d) The cell proliferation of PFC cells were examined by CCK-8 assay. vs. PFC group. vs. PFC + BLM group. (e) The cell apoptosis of PFC cells were examined by CCK-8 assay. vs. PFC group. , vs. PFC + BLM group.

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