Analyzing Prognostic Hub Genes in the Microenvironment of Cutaneous Melanoma by Computer Integrated Bioinformatics

Figure 1

Immune scores and stromal scores are associated with CM pathological types and their overall survival. (a) Distribution of immune scores of CM pathological types. Violin plot shows that there is significant association between CM pathological types and immune scores . (b) Distribution of stromal scores of CM pathological types. Violin plot shows that there is significant association between CM pathological types and stromal scores . (c) Distribution of immune scores for BRAF mutant and BRAF wildtype CM cases. Violin plot shows that there is no significant association between BRAF mutation status and immune scores . (d) Distribution of stromal scores for BRAF mutant and BRAF wildtype CM cases. Violin plot shows that there is no significant association between BRAF mutation status and stromal scores . (e) CM cases were divided into two groups based on their immune scores: the top half of 235 cases with higher immune scores and the bottom half of 235 cases with lower immune scores. As shown in the Kaplan–Meier survival curve, median survival of the high score group is longer than low-score group . (f) Similarly, CM cases were divided into two groups based on their stromal scores: the top half of 235 cases and the bottom half of 235 cases. The median survival of the high score group is longer than the low-score group .

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