Hispidulin Enhances Temozolomide (TMZ)-Induced Cytotoxicity against Malignant Glioma Cells In Vitro by Inhibiting Autophagy

Figure 1

Cytotoxicity of hispidulin, TMZ, or their combination on U87MG cells. (a) Cytotoxicity of hispidulin (5, 10, 20, 40, and 100 μg/ml) on U87MG cells. (b) Cytotoxicity of TMZ (50, 100, 200, 400, and 800 μM) on U87MG cells. (c) Cytotoxicity of hispidulin (40 μg/ml) and temozolomide (50, 100, and 200 μM) on U87MG cells. The data are expressed as the mean ± SD (n = 3). , , and vs. control.

(a)

(b)

(c)