Research Article
[Retracted] Celecoxib Reverse Invasion and Metastasis of Gastric Cancer through Lnc_AC006548.28-miR-223-LAMC2 Pathway
Figure 4
Celecoxib exerts antitumor effect through Lnc_ AC006548.28-miR-223-LAMC2 pathway. (a and c) After the treatment with celecoxib or KO Lnc_AC006548.28, OE-miR-223, and KO LAMC2 detected the tumor infiltration by HE staining. The difference was statistically significant. (b and d) Ki67 was used to detect the proliferation of cancer cells; the same results were those that suggest LAMC2 may regulate Lnc_AC006548.28 by regulating miR-223 expression and affect the pathological progress of tumor. (e) Suitable primers were designed. (f) The expression of genes in different groups was detected by PCR test, the difference was statistically significant, and the expression of these genes had the role of mutual regulation.
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