[Retracted] LncXIST Facilitates Iron Overload and Iron Overload-Induced Islet Beta Cell Injury in Type 2 Diabetes through miR-130a-3p/ALK2 Axis

Figure 5

miR-130a-3p directly binds to and regulates the expression of ALK2. (a) The predicted binding sites of miR-130a-3p to ALK2 sequence using StarBase. ((b) and (c)) The expression of ALK2 protein was detected by Western blot. (d) The relative luciferase of HEK 923 cells was transfected with miR-130a-3p mimics or inhibitors and luciferase constructs of WT- or MUT-ALK2-UTR.  < 0.01.

(a)

(b)

(c)

(d)