Research Article

[Retracted] C-Reactive Protein as a Prognostic Biomarker for Gynecologic Cancers: A Meta-Analysis

Table 1

Main characteristics of studies included in this meta-analysis.

First author, publication yearCountryRecruitment periodAge (mean/median) yrNo. ptsCancer typePathologyStageSurvival analysisMean/median months of follow-upNOS scores

Schmid et al. 2007 [36]Austria1995–2005NM403ECADCFIGO I-IVOS,DFSNM6
Six et al. 2008 [33]Austria1995–200369.167VCSCCFIGO I-IVOS,DFSNM7
Hefler et al. 2008 [28]AustriaNM60.5623OCSerous, mucinous, endometrioid, clear cell, and othersFIGO I-IVOS25.57
Stephan et al. 2011 [23]Austria2000–200949.2178CCSCC and non-SCCFIGO I-IVOS,DFS468
Dobrzycka et al. 2013 [27]Poland2003–200757.6118OCSerous, mucinous, endometrioid, clear cell, and othersFIGO I-IVOS,DFS24.638
Nakamura et al. 2015 [21]Japan2005–201452.632CCSCC and non-SCCNMOSNM7
Zhang et al. 2015 [29]China2000–201250.6190OCSerous, mucinous, endometrioid, clear cell, and othersFIGO I-IVOS,PFS438
Lu et al. 2015 [31]China2006–201055.28107OCserous, mucinous, endometrioid, clear cell, and othersFIGO I-IVOS28.58
Li et al. 2015 [34]China2007–200953282ECEndometrioid and othersFIGO I-IVDSS51.28
Xiao et al. 2015 [26]China2004–201152238CCSCC, non-SCCFIGO IB1-IVAOS,PFS428
Bodner–Adler et al. 2016[19]Austria2005–20155146CCADCFIGO I-IVOSNM7
Liu et al. 2017 [32]China2006–201253200OCSerous, mucinous, endometrioid, clear cell, and othersFIGO I-IVOSNM8
He et al. 2018 [25]China2007–200969198CCSCCFIGO I-IVOSNM8
Wang et al. 2019 [24]China2012–201451.5110CCSCCFIGO I-IIOS,PFSNM8
Wang et al. 2020 [20]China2013–201559150CCSCCFIGO IB2,IIA2-IIB, IIIOS398
An et al. 2020 [22]China2010–201745.5278CCSCC, non-SCCFIGO IB-IIAOS,RFSNM8
Terlikowska et al. 2020[35]Poland2006–201269176ECADCFIGO I-IVOSNM7
Komura et al. 2020[30]Japan2007–2016NM308OCSerous, mucinous, endometrioid, clear cell, othersFIGO I-IVDSSNM6
Njoku et al. 2021 [37]United Kingdom2010–201566358ECEndometrioid and othersFIGO I-IVOS,RFS408

Abbreviations: ADC: adenocarcinoma; CC: cervical cancer; DFS: disease-free survival; DSS: disease-specific survival; EC: endometrial cancer; FIGO: International Federation of Gynecology and Obstetrics; NM: not mentioned; OC: ovarian cancer; OS: overall survival; PFS: progress-free survival; RFS: recurrence-free survival; SCC: squamous cell carcinoma; VC: vulvar cancer.