Diagnosis of Chronic Obstructive Pulmonary Disease and Regulatory Mechanism of miR-149-3p on Alveolar Inflammatory Factors and Expression of Surfactant Proteins A (SP-A) and D (SP-D) on Lung Surface Mediated by Wnt Pathway
Table 2
Comparison of general information and lung function between groups.
Item
CON
COPD
Statistics
Age (years)
66.26 ± 8.51
65.84 ± 7.00
0.816
0.444
Gender (case/%)
Male
33 (66%)
34 (68%)
0.434
0.805
Female
17 (34%)
16 (32%)
Smoking index [M (Q1, Q3)]
265 (120, 340)
420a (320, 585)
28.612
<0.001
Number of acute exacerbations in the past year [times, M (Q1, Q3)]
—
1.0 (1.0, 2.0)
−3.802
<0.001
mMRC score [score, M (Q1, Q3)]
—
1.0 (1.0, 2.0)
−6.259
<0.001
FEV1% predicted value
80.69 ± 7.62
54.21 ± 6.76
277.513
<0.001
FEV1/FVC (%)
83.44 ± 5.96
51.56 ± 6.29a
373.072
<0.001
a, compared with the Con group; indicates Welch analysis of variance.
