Optimisation of a Mouse Model of Cerebral Ischemia-Reperfusion to Address Issues of Survival and Model Reproducibility and Consistency

Figure 3

Percentage decrease in MCA blood flow. (a) No significant difference in the percentage decrease in MCA flow between the groups ICA1, ICA2, ECA1, and ECA2 after monofilament insertion,  > 0.05, n = 15. (b) 80 minutes after insertion of the monofilament, the percentage decrease in MCA flow was significantly greater in ICA1 and ECA1 than in ICA2 and ECA2.  < 0.05, n = 15, while there was no significant difference between groups 1 and 2  > 0.05, n = 15. Values are expressed as mean ± SD.

(a)

(b)