Optimisation of a Mouse Model of Cerebral Ischemia-Reperfusion to Address Issues of Survival and Model Reproducibility and Consistency

Figure 7

Survival rates between groups at different time points postoperatively. (a) No statistically significant difference in survival rate between groups at 24 h postoperatively  > 0.05, n = 15. (b) At 72 h postoperatively, the survival rate in the ECA1 group was significantly lower than that in the ICA1 and ICA2 groups,  < 0.05, n = 15, the survival rate in the ECA2 group was significantly lower than that in the ICA1 and ICA2 groups  < 0.01. n = 15 (c) At 1 week postoperatively, there was no difference in survival rates between the ECA1 and ECA2 groups, and similarly between the ICA1 and ICA2 groups,  > 0.05, n = 15. survival rates in the ICA2 group were significantly higher than those in the ECA1 and ECA2 groups  < 0.01. n = 15.

(a)

(b)

(c)