Research Article

[Retracted] A Novel Artificial Intelligence System in Formulation Dissolution Prediction

Table 1

The comparison of related projects.

ProjectsANN modelRegression methodInput and outputAmounts of parameters and samples

This projectANN with backpropagation networkEDRM and RLRMInput: the factors of tablets and the time points of dissolution. Output: dissolution results in every time points.21 samples and 7 parameters. 3 kinds of formulation composition
Yixin Chen’s project [17]No algorithm is shown in the studyThe average value of 10 times predictionInput: the factors of tablets. Output: dissolution result of a single time point22 samples and 4 parameters
Jothi G. Kesavan’s project [18]PROC REGInput: hardness, friability, and thickness. Output: disintegration time23 samples and 3 parameters
Uttam MANDAL’s project [19]ANN using multilayer perceptronsHiguchi equationInput: the composition of tablets. Output: dissolution result of a single time point.13 samples and 3 parameters