Biological Mechanism on SIRT1/NLRP3/IL-18 Signaling Pathway of Acupuncture for Treatment of Ischemic Stroke with Center Poststroke Pain

<div>KEGG Pathview analysis of molecular signature of NLRP3 inflammasome signaling pathway, (a) Pathview analysis of siSIRT1 group compared to Control group; (b) Pathview analysis of NLRP3 reconstituted group compared to NLRP3 KO group; KEGG pathway analysis demonstrating upregulation or downregulation of multiple components of the complement pathway. Each box was one gene; the green boxes show the downregulated gene expression of mRNA while the red boxes show the upregulated gene expression.</div>

Computational Intelligence and Neuroscience

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Figure 2

Figure 2: Biological Mechanism on SIRT1/NLRP3/IL-18 Signaling Pathway of Acupuncture for Treatment of Ischemic Stroke with Center Poststroke Pain 