Biological Mechanism on SIRT1/NLRP3/IL-18 Signaling Pathway of Acupuncture for Treatment of Ischemic Stroke with Center Poststroke Pain

<div>Changes in mechanical pain threshold in rats after establishing a central pain model after stroke. Compared with the Sham group, the MWT value of the left plantar in the CPSP group was decreased (<i>P</i> &lt; 0.05); compared with the CPSP group, the MWT value in the AP group was increased (<i>P</i> &lt; 0.05); compared with the AP group, MWT value in EX527 group was increased (<i>P</i> &lt; 0.05).</div>

Computational Intelligence and Neuroscience

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Figure 3

Figure 3: Biological Mechanism on SIRT1/NLRP3/IL-18 Signaling Pathway of Acupuncture for Treatment of Ischemic Stroke with Center Poststroke Pain 