Research Article
A Nomogram Based on CT Radiomics and Clinical Risk Factors for Prediction of Prognosis of Hypertensive Intracerebral Hemorrhage
Table 1
The clinical characteristics of the training cohort and the validation cohort.
| Characteristics | Training cohort (n = 138) | | Validation cohort (n = 57) | | Favorable outcome (n = 49) | Unfavorable outcome (n = 89) | Favorable outcome (n = 20) | Unfavorable outcome (n = 37) |
| Sex (n, %) | | | 0.037 | | | 0.604 | Female | 10 (20.4) | 35 (39.3) | | 13 (65.0) | 20 (54.1) | | Male | 39 (79.6) | 54 (60.7) | | 7 (35.0) | 17 (45.9) | | Age (year) | 51.6 ± 11.6 | 63.7 ± 12.0 | <0.001 | 53.9 ± 11.0 | 62 ± 13.3 | 0.020 | SBP (mmHg) | 165.8 ± 27.3 | 163.6 ± 25.1 | 0.637 | 158.7 ± 25.0 | 167.6 ± 33.2 | 0.294 | DBP (mmHg) | 98.1 ± 19.2 | 96.0 ± 16.5 | 0.493 | 93.5 ± 13.4 | 93.4 ± 16.5 | 0.998 | Smoking (n, %) | | | 1.000 | | | 0.623 | No | 31 (63.3) | 56 (62.9) | | 12 (60.0) | 26 (70.3) | | Yes | 18 (36.7) | 33 (37.1) | | 8 (40.0) | 11 (29.7) | | Drinking (n, %) | | | 0.223 | | | 0.544 | No | 22 (44.9) | 51 (57.3) | | 10 (50.0) | 23 (62.2) | | Yes | 27 (55.1) | 38 (42.7) | | 10 (50.0) | 14 (37.8) | | Diabetes (n, %) | | | 0.050 | | | 0.482 | No | 46 (93.9) | 71 (79.8) | | 17 (85.0) | 27 (73.0) | | Yes | 3 (6.1) | 18 (20.2) | | 5 (15.0) | 10 (27.0) | | Monocyte count (109/L) | 0.4 ± 0.2 | 0.5 ± 0.3 | 0.084 | 0.6 ± 0.2 | 0.5 ± 0.3 | 0.446 | WBC (109/L) | 10.3 ± 4.0 | 11.9 ± 4.9 | 0.048 | 11.3 ± 3.9 | 12.0 ± 4.9 | 0.571 | Lymphocyte count (109/L) | 1.3 ± 0.9 | 1.3 ± 0.9 | 0.760 | 1.3 ± 0.5 | 1.2 ± 0.8 | 0.493 | RBC (1012/L) | 4.8 ± 0.6 | 4.5 ± 0.6 | 0.037 | 4.6 ± 0.6 | 4.7 ± 0.7 | 0.648 | Platelet count (109/L) | 224.6 ± 60.6 | 229.0 ± 78.8 | 0.732 | 230.5 ± 49.8 | 227.4 ± 74.6 | 0.866 | Hemoglobin (g/L) | 143.1 ± 22.2 | 137.9 ± 18.8 | 0.150 | 142.5 ± 17.0 | 142.4 ± 17.9 | 0.986 | Serum glucose (mmol/L) | 7.5 ± 2.9 | 9.1 ± 3.6 | 0.007 | 8.3 ± 4.0 | 10.5 ± 3.7 | 0.031 | D-dimer (mg/L) | 0.5 ± 0.5 | 1.9 ± 4.3 | 0.022 | 0.6 ± 0.4 | 1.8 ± 2.0 | 0.006 | Volume of hematoma (mL) | 15.2 ± 13.2 | 30.8 ± 23.1 | <0.001 | 15.1 ± 8.8 | 30.5 ± 22.7 | 0.003 | Location (n, %) | | | 0.698 | | | 0.197 | Basal ganglia | 41 (83.7) | 69 (77.5) | | 17 (85.0) | 25 (67.6) | | Lobe | 6 (12.2) | 12 (13.5) | | 2 (10.0) | 2 (5.4) | | Brainstem | 0 (0.0) | 1 (1.1) | | 0 (0.0) | 6 (16.2) | | Cerebellum | 2 (4.1) | 7 (7.9) | | 1 (5.0) | 4 (10.8) | | Intraventricular hemorrhage (n, %) | | | 0.059 | | | 0.064 | No | 31 (63.3) | 40 (44.9) | | 14 (70.0) | 15 (40.5) | | Yes | 18 (36.7) | 49 (55.1) | | 6 (30.0) | 22 (59.5) | | Midline shift (n, %) | | | 0.006 | | | 0.833 | No | 33 (67.3) | 37 (41.6) | | 10 (50.0) | 16 (43.2) | | Yes | 16 (32.7) | 52 (58.4) | | 10 (50.0) | 21 (56.8) | | Herniation | | | 0.552 | | | 0.191 | No | 46 (93.8) | 81 (91.0) | | 20 (100.0) | 34 (91.9) | | Yes | 3 (6.2) | 8 (9.0) | | 0 (0.0) | 3 (8.1) | | Ventricular entrapment | | | 0.061 | | | 0.105 | No | 43 (87.8) | 66 (72.2) | | 19 (95.0) | 31 (83.8) | | Yes | 6 (12.2) | 23 (25.8) | | 1 (5.0) | 6 (16.2) | | Rad-score | −0.6 (−1.3, 0.3) | 1.6 (0.6, 3.1) | <0.001 | −1.3 (−1.7,−0.2) | 1.3 [0.2, 2.4] | <0.001 |
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Notes. < 0.05, indicating that the difference was statistically significant. SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell; RBC, red blood cell; Rad-score, radiomics score. |