Research Article
[Retracted] A Potential Prognostic Biomarker for Glioma: Aldo-Keto Reductase Family 1 Member B1
Table 1
The characteristics of patients with glioma based on TCGA.
| | Characteristic | Low expression of AKR1B1 | High expression of AKR1B1 | |
| | n | 348 | 348 | | | WHO grade, n (%) | | | <0.001 | | G2 | 160 (25.2%) | 64 (10.1%) | | | G3 | 132 (20.8%) | 111 (17.5%) | | | G4 | 17 (2.7%) | 151 (23.8%) | | | IDH status, n (%) | | | <0.001 | | WT | 61 (8.9%) | 185 (27%) | | | Mut | 284 (41.4%) | 156 (22.7%) | | | 1p/19q codeletion, n (%) | | | <0.001 | | Codel | 133 (19.3%) | 38 (5.5%) | | | Non-codel | 215 (31.2%) | 303 (44%) | | | Primary therapy outcome, n (%) | | | 0.004 | | PD | 55 (11.9%) | 57 (12.3%) | | | SD | 100 (21.6%) | 47 (10.2%) | | | PR | 42 (9.1%) | 22 (4.8%) | | | CR | 96 (20.8%) | 43 (9.3%) | | | Gender, n (%) | | | 0.146 | | Female | 139 (20%) | 159 (22.8%) | | | Male | 209 (30%) | 189 (27.2%) | | | Race, n (%) | | | 0.383 | | Asian | 4 (0.6%) | 9 (1.3%) | | | Black or African American | 16 (2.3%) | 17 (2.5%) | | | White | 319 (46.7%) | 318 (46.6%) | | | Age, n (%) | | | <0.001 | | ≤60 | 305 (43.8%) | 248 (35.6%) | | | >60 | 43 (6.2%) | 100 (14.4%) | | | Histological type, n (%) | | | <0.001 | | Astrocytoma | 110 (15.8%) | 85 (12.2%) | | | Glioblastoma | 17 (2.4%) | 151 (21.7%) | | | Oligoastrocytoma | 81 (11.6%) | 53 (7.6%) | | | Oligodendroglioma | 140 (20.1%) | 59 (8.5%) | | | Age, median (IQR) | 40 (32, 53) | 51 (38, 62) | <0.001 |
|
|
