Research Article

Supervised Machine Learning Based Noninvasive Prediction of Atrial Flutter Mechanism from P-to-P Interval Variability under Imbalanced Dataset Conditions

Table 11

Related works on discrimination of AFL mechanism (PWM: P-wave morphology, CL: cycle length, and NA: not applicable).

AuthorYearRatio macro/focal (ECGs)TechniqueClassifierParameter (significant)Performance

Brown et al.200727/14PWM, CLNA (autocorrelation performed)P < 160 ms P/CL < 45%P:
Sensitivity: 90%
Specificity: 90%
P/CL:
Sensitivity: 86%
Specificity: 98%

Chang et al.201151/17PWM CLNA (empirical-based study)V6 > 0.9 mV, CL > 265 ms V6 < 0.9 mV, CL > 290 msAccuracy focal: 93%
Accuracy macro: 88%
Accuracy focal: 100%
Accuracy macro: 100%

Luongo et al.2020Original: 11/9
Augmented: 1256
Recurrance quantificationDecision tree (DT), KNN, and radial basis neural network (rbNN)RQA-based featuresHit rate: 67.7%

Proposed modelOriginal: 41/5
Augmented: 15 (focal)
Consecutive P-P intervals (within R-R interval)LDA, LOG, and SVMSum of all consecutive intervals (p < 0.05)Accuracy: 76.88%
Specificity: 49.50
Sensitivity: 90.24%