Elevated Serum Levels of the Antiapoptotic Protein Decoy-Receptor 3 Are Associated with Advanced Liver Disease

Figure 2

Serum concentration of DcR3 strongly correlates with markers of disease progression in patients with chronic liver disease. The serum concentration of DcR3 was measured by ELISA. Ishak scores (histological stage) were retrieved from the histological reports from patients with available liver biopsies. MELD scores were calculated for cirrhotic patients. The correlation of sDcR3 concentration with (a) the MELD score of patients with cirrhosis is shown; (b) the liver stiffness values of patients with chronic liver disease as measured by shear wave elastography. Statistical significance of correlation was calculated by use of Spearman’s -test.

(a)

(b)