Comparison of One versus Two Fecal Immunochemical Tests in the Detection of Colorectal Neoplasia in a Population-Based Colorectal Cancer Screening Program

Table 1

Positive predictive value of one versus two positive FITs.

Pathology	Two positive FITs	PPV (95% CI)	One positive FIT	PPV (95% CI)	Total	value
Cancer	45	8% (6%, 11%)	13	1% (1%, 2%)	58	<0.0001
High-risk polyp	210	40% (36%, 44%)	209	20% (18%, 22%)	419	<0.0001
Any neoplasia	352	67% (63%, 71%)	499	48% (45%, 51%)	851	<0.0001