Abdominal Symptoms and Incident Gallstones in a Population Unaware of Gallstone Status

Table 2

Logistic regression analyses of changes in abdominal pain between baseline and follow-up in incident gallstone disease.

	Incident gallstones or cholecystectomy group (%)	No gallstones group (%)	Unadjusted OR; 95% CI^1	Adjusted OR; 95% CI^1,2	Sensitivity analysis: without cholecystectomy^2,3	Sensitivity analysis: without stone awareness^2,4
Remained symptom-free	122 (47.7)	1,240 (47.8)	Ref.	Ref.	Ref.	Ref.
Became symptom-free	51 (19.9)	633 (24.4)	0.82 [0.58; 1.15]	0.91 [0.64; 1.30]	0.90 [0.63; 1.28]	0.92 [0.64; 1.33]
Persisting symptoms	63 (24.6)	473 (18.2)	1.35 [0.98; 1.87]	1.20 [0.86; 1.68]	1.13 [0.80; 1.59]	1.10 [0.77; 1.56]
Symptom debut	20 (7.8)	246 (9.5)	0.83 [0.51; 1.35]	0.70 [0.42; 1.16]	0.67 [0.40; 1.11]	0.64 [0.38; 1.09]

(total) = 2,848 (minus missing in adjusted analyses), (incident stones) = 250, (cholecystectomy) = 6, and (stone-free) = 2,592.
Adjusted for baseline sex, age, BMI (interaction with sex), units of alcohol per week, social groups I + II–V, cohabitant status, and changes in consumption of alcohol units per week (interactions with sex).
(total) = 2,842, (incident stones) = 250, and (stone-free) = 2,592.
(total) = 2,805, (incident stones) = 239, and (stone-free) = 2,565.