Microsatellite Instability in Mouse Models of Colorectal Cancer

Figure 2

The length of the Bat59 mononucleotide repeat varies slightly within individual Msh2-KO mice. (a, e) Bat59 in the colon of two WT mice; (b–d); (f–h) Bat59 in the proximal, mid, and distal colon of two Msh2-KO mice. The position of the highest peak in the WT mouse is highlighted with the grey bar; 187 bp refers to the size of the PCR fragment in the WT and the number in the top right corner indicates the number of nucleotides by which the repeat is shortened in each Msh2-KO mouse.