Expression Analysis of ATP-Binding Cassette Transporters ABCB11 and ABCB4 in Primary Sclerosing Cholangitis and Variety of Pediatric and Adult Cholestatic and Noncholestatic Liver Diseases

<div>Immunohistochemical staining for ABCB11 in FFPE liver sections of FNH, chronic hepatitis C, NASH, Alagille syndrome (NC3), PFIC (NC1), TPN-related liver disease (NC2), PCLD, and PSC. ABCB11 stained in brown; nuclei stained with hematoxylin in blue. In PSC, high expression and accumulation of ABCB11 at the bile canalicular membrane of adjacent hepatocytes were most consistent between different cholestatic liver diseases. Scale bar = 20 <i>μ</i>m.</div>

Canadian Journal of Gastroenterology and Hepatology

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Figure 1: Expression Analysis of ATP-Binding Cassette Transporters ABCB11 and ABCB4 in Primary Sclerosing Cholangitis and Variety of Pediatric and Adult Cholestatic and Noncholestatic Liver Diseases 

Figure 1 | Expression Analysis of ATP-Binding Cassette Transporters ABCB11 and ABCB4 in Primary Sclerosing Cholangitis and Variety of Pediatric and Adult Cholestatic and Noncholestatic Liver Diseases 