Research Article
Expression Analysis of ATP-Binding Cassette Transporters ABCB11 and ABCB4 in Primary Sclerosing Cholangitis and Variety of Pediatric and Adult Cholestatic and Noncholestatic Liver Diseases
Figure 2
Immunohistochemical staining for ABCB4 in FFPE liver sections of FNH, chronic hepatitis C, NASH, Alagille syndrome (NC3), PFIC (NC1), TPN-related liver disease (NC2), PCLD, and PSC. ABCB4 stained in brown; nuclei stained with hematoxylin in blue. In PSC, high expression and accumulation of ABCB4 at the bile canalicular membrane of adjacent hepatocytes were mostly consistent within the group of cholestatic liver diseases. Scale bar = 20 μm.