Expression Analysis of ATP-Binding Cassette Transporters ABCB11 and ABCB4 in Primary Sclerosing Cholangitis and Variety of Pediatric and Adult Cholestatic and Noncholestatic Liver Diseases

Figure 4

Comparative expression analysis of RNA levels of ABCB11 in LCM hepatocytes of FFPE liver explants from PSC patients (PSC, ) and patients with non-PSC liver diseases (Other, ). nCounter analysis revealed significantly differential expressed RNA levels of the ABCB11 gene between the 2 patient cohorts. ABCB11 is higher expressed in hepatocytes of PSC patients when compared to the control group (Other). values were determined by an unpaired t test (two-tailed) ().