Research Article
FLOT Neoadjuvant Chemotherapy Followed by Laparoscopic D2 Gastrectomy in the Treatment of Locally Resectable Advanced Gastric Cancer
Table 2
Adverse events during neoadjuvant chemotherapy (n = 23).
| | Toxicities | Grade 1-2 | Grade 3 | Grade 4 | % grade 3/4 |
| | Hematologic | | | 0 | | | Leukopenia | 6 | 4 | 0 | 17.4 | | Neutropenia | 7 | 7 | 0 | 30.4 | | Thrombocytopenia | 0 | 0 | 0 | 0 | | Anemia | 4 | 3 | 0 | 13.0 |
| | Gastrointestinal | | | | | | Nausea | 10 | 3 | 1 | 17.4 | | Vomiting | 5 | 1 | 1 | 8.7 | | Diarrhea | 6 | 1 | 0 | 4.3 | | Constipation | 4 | 2 | 0 | 8.7 | | Anorexia | 3 | 3 | 0 | 13.0 |
| | Laboratory | | | | | | AST | 5 | 0 | 0 | 0 | | ALT | 5 | 0 | 0 | 0 |
| | Fatigue | 2 | 0 | 0 | 0 | | Neurosensory | 1 | 0 | 0 | 0 |
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AST, aspartate transaminase; ALT, alanine transaminase.
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