The Prevalence, Predictors, and In-Hospital Mortality of Hepatic Encephalopathy in Patients with Liver Cirrhosis Admitted at St. Dominic Hospital in Akwatia, Ghana

Table 6

Laboratory parameters of the study participants.

Liver function	Encephalopathy (present) (n = 53)	Encephalopathy (absent) (n = 114)	value
AST (U/L)	142.7 (4.7, 280.7)	109.7 (25.7, 193.7)	0.067
ALT (U/L)	72.5 (10.7, 134.3)	61.8 (16, 107)	0.211
ALP (U/L)	471.2 (2.3, 940.1)	384.6 (13.1, 756.1)	0.240
GGT (U/L)	336.7 (4.5, 668.9)	231.6 (7, 456.2)	0.026
Total bilirubin (μmol/l)	150.3 (5.2, 295.4)	82.6 (−43.3, 208.5)	0.002
Total protein (g/l)	69.3 (54, 84.4)	69.3 (53, 85.3)	0.959
Serum albumin (g/l)	25.5 (18, 32.9)	29.4 (21.5, 37.4)	0.003
INR	3 (1.8, 4.2)	2.1 (1.4, 2.8)	<0.001
CPS	12 (9.9, 14.3)	9.4 (7.3, 11.5)	< 0.001
MELD-Na	31 (23.5, 38.5)	22 (15.2, 28.8)	<0.001
Full blood count
Haemoglobin (g/dl)	9.3 (1.8, 15.6)	10.2 (2.3, 17.2)	0.053
White blood cell (10^9/l)	10.9 (1.3, 38.2)	13 (1.6, 438)	0.717
Platelet count (10^9/l)	130.6 (7, 515)	176.3 (5.90, 705)	0.015
Renal function test
Sodium (mmol/l)	130.4 (97.1, 146.7)	134 (118, 151)	<0.001
Potassium (mmol/l)	3.9 (2.1, 6.4)	4.1 (2, 7.2)	0.313
BUN (μmol/l)	11.3 (1.6, 21)	7.2 (−1.0, 15.4)	0.006
Creatinine (μmol/l)	157.9 (22.7, 625.3)	108 (21.4, 815.8)	0.010

ALT—alanine aminotransferase; ALP—alkaline phosphatase; GGT—gamma glutamyl transferase; AST—aspartate aminotransferase; BUN—blood urea nitrogen; MELD-Na—model for end-stage liver disease sodium; INR—international normalized ration; CPS—Child–Pugh score.