Association and Prediction of Subclinical Atherosclerosis by Nonalcoholic Fatty Liver Disease in Asymptomatic Patients
Table 2
Summary of the regression analysis of the correlation between coronary stenosis and NAFLD.
Model 1
Model 2
OR (95% CI)
value
for trend
OR (95% CI)
value
for trend
NAFLD
Grade 0
1
(Reference)
—
—
1
(Reference)
—
—
Grade 1
2.12
(1.53–2.97)
<0.001
<0.001
1.69
(1.19–2.41)
0.004
0.013
Grade 2
2.39
(1.71–3.35)
<0.001
1.56
(1.06–2.29)
0.023
Grade 3
4.04
(2.23–8.11)
<0.001
2.25
(1.05–4.80)
0.037
Age (years)
1.09
(1.07–1.10)
<0.001
1.09
(1.07–1.11)
<0.001
Sex
0.45
(0.34–0.60)
<0.001
0.51
(0.37–0.69)
<0.001
BMI (kg/m2)
—
—
—
1.00
(0.95–1.05)
0.960
HbA1c
—
—
—
1.38
(1.21–1.58)
<0.001
TC (mg/dL)
—
—
—
1.01
(1.00–1.01)
0.001
HDL (mg/dL)
—
—
—
0.98
(0.97–0.99)
<0.001
SBP (mmHg)
—
—
—
1.00
(0.99–1.01)
0.403
Hypertension
—
—
—
2.05
(1.48–2.85)
<0.001
Smoking status
—
—
—
1.79
(1.24–2.60)
0.002
NAFLD: nonalcoholic fatty liver disease; OR: odds ratio; CI: confidence interval; BMI: body mass index; TC: total cholesterol; HDL: high-density lipoprotein cholesterol; SBP: systolic blood pressure. Model 1 included age and sex. Model 2 included BMI, HbA1c, and Framingham risk factors (total cholesterol, HDL cholesterol, SBP, hypertension status, and smoking status) in addition to the variables addressed in Model 1.