Research Article
Risk of Hepatocellular Carcinoma Remains High in Patients with HBV-Related Decompensated Cirrhosis and Long-Term Antiviral Therapy
Table 2
Risk factors for HCC development in patients with hepatitis B virus-related decompensated cirrhosis.
| Variables | Univariate analysis | Multivariate analysis | OR (95% CI) | value | OR (95% CI) | value |
| Age | 2.994 (1.240–7.227) | 0.02 | 2.987 (1.301–6.858) | 0.01 | Sex | 2.561 (1.055–6.220) | 0.04 | 2.408 (1.126–5.149) | 0.02 | ALT (U/L) | 0.996 (0.987–1.005) | 0.35 | | | Total bilirubin (μmol/L) | 1.006 (0.987–1.026) | 0.54 | | | Cholinesterase (U/L) | 1.000 (0.999–1.000) | 0.50 | | | Platelet counts (E + 09/L) | 1.000 (0.994–1.007) | 0.89 | | | INR | 0.408 (0.062–2.674) | 0.35 | | | Sodium (mmol/L) | 1.122 (0.968–1.301) | 0.13 | | | Creatinine (μmol/L) | 0.998 (0.978–1.0191) | 0.86 | | | AFP (ng/ml) | 0.998 (0.998–1.002) | 0.77 | | |
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Abbreviations: ALT, alanine aminotransferase; INR, prothrombin time/international normalized ratio; AFP, alpha-fetoprotein.
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