Adherence to Azathioprine/6-Mercaptopurine in Children and Adolescents with Inflammatory Bowel Diseases: A Multimethod Study

Figure 2

Scatter plot showing the four different clusters formed after clustering of the IBD study sample (n = 45) using 20th percentile of metabolite levels as cut-off point. Data for 6-mMPNs and 6-TGNs are the metabolite levels (adjusted per dose/SA). Cluster (A) (i.e., above 20% cut-off point) was characterized by high levels of 6-TGN and 6-mMP (adherent patients). Cluster (B) was characterized by high levels of 6-mMP but with low 6-TGN concentrations. Cluster (C) was characterized by low levels of both 6-mMP and 6-TGN (nonadherent patients). Cluster (D) patients have low levels of 6-mMP and high levels of 6-TGN.