Nomogram to Predict the Survival of Chinese Patients with Alcohol-Related Liver Disease

Table 2

Univariable analysis of ALD patients in the training cohort.

Variable	HR	95% CI	value
Clinical characteristics
Age, years	0.986	0.968–1.005	0.147
Male, n%	2.183	0.312–15.259	0.431
Relapse, n%	2.781	1.682–4.601	<0.001
Smoking, n%	1.085	0.683–1.724	0.728
Cirrhosis, n%	8.791	2.785–27.748	<0.001
AH, n%	2.461	1.643–3.687	<0.001
Cancer, n%	3.462	2.016–5.946	<0.001
Ascites, n%	3.011	1.759–5.156	<0.001
Varices bleeding, n%	1.166	0.636–2.136	0.619
Encephalopathy, n%	1.917	1.170–3.141	0.010
Laboratory parameters
WBC (10^9/L)	1.020	0.987–1.053	0.245
HB (g/L)	0.993	0.986–1.000	0.036
PLT (g/L)	0.996	0.993–0.999	0.014
ALT (U/T)	0.999	0.998–1.000	0.204
AST (U/T)	1.000	1.000–1.001	0.061
TBIL (μmol/L)	1.004	1.003–1.006	<0.001
ALB (g/L)	0.908	0.876–0.940	<0.001
Cr (μmol/L)	1.007	1.005–1.009	<0.001
PT-INR	2.098	1.580–2.788	<0.001
Na (mmol/L)	0.985	0.977–0.992	<0.001
Scoring system
MELD ≥21, n%	3.235	2.056–5.090	<0.001

value <0.05 was considered significant. CI, confidence interval; AH, alcoholic hepatitis; WBC, white blood cell; HB, haemoglobin; PLT, platelet count; ALT, alanine transaminase; AST, aspartate transaminase; TBIL, total bilirubin; ALB, albumin; Cr, creatine; PT-INR, prothrombin time-International Standardization Ratio; MELD score, model for end-stage liver diseases score.