Research Article
Therapeutic Decision Making in Hepatocellular Carcinoma According to Age and Child–Pugh Class: A Nationwide Cohort Analysis in South Korea
Table 1
Patient characteristics (n = 7559).
| | Variables | All patients | Single tumor | PVT-positive tumor | | n = 7559 | n = 4633 | n = 625 |
| | Age | | Median (range) | 60 (21–98) | 61 (22–91) | 57 (28–92) | | ≤59 | 3577 (47.3%) | 2182 (47.1%) | 366 (58.6%) | | 60–69 | 2180 (28.8%) | 1355 (29.2%) | 145 (23.2%) | | ≥70 | 1802 (23.8%) | 1096 (23.7%) | 114 (18.2%) |
| | Sex | | Male | 5838 (77.2%) | 3471 (74.9%) | 527 (84.3%) | | Female | 1721 (22.8%) | 1162 (25.1%) | 98 (15.7%) |
| | Child–Pugh class | | A | 5855 (77.5%) | 3850 (83.1%) | 327 (52.3%) | | B | 1422 (18.8%) | 667 (14.4%) | 241 (38.6%) | | C | 282 (3.7%) | 116 (2.5%) | 57 (9.1%) | | Hepatitis B | 4507 (59.6%) | 1736 (37.5%) | 413 (66.1%) | | Hepatitis C | 983 (13.0%) | 581 (12.5%) | 69 (11.0%) | | Non-B, non-C | 267 (3.5%) | 165 (3.6%) | 17 (2.7%) |
| | ECOG performance status | | 0 | 4310 (57.0%) | 2827 (61.0%) | 252 (40.3%) | | 1 | 798 (10.6%) | 395 (8.5%) | 127 (20.3%) | | 2 | 154 (2.0%) | 51 (1.1%) | 38 (6.1%) | | 3 | 55 (0.7%) | 12 (0.3%) | 23 (3.7%) | | 4 | 37 (0.5%) | 8 (0.2%) | 10 (1.6%) | | NA | 2205 (29.2%) | 1340 (28.9%) | 175 (28.0%) |
| | Tumor size (cm) | | ≤2 cm | 2746 (36.3%) | 2018 (43.6%) | 53 (8.5%) | | >2 cm | 4813 (63.7%) | 2615 (56.4%) | 572 (91.5%) |
| | Number of tumors | | ≤4 | 6511 (86.1%) | 4633 (100.0%) | 204 (32.6%) | | >4 | 1048 (13.9%) | 0 (0.0%) | 421 (67.4%) |
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ECOG, Eastern Cooperative Oncology Group; PVT, portal vein tumor thrombosis; NA, not available.
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