Research Article

Therapeutic Decision Making in Hepatocellular Carcinoma According to Age and Child–Pugh Class: A Nationwide Cohort Analysis in South Korea

Table 2

Treatment pattern change by age and the Child–Pugh classification in single lesions.

Treatment n = 4601Age (years)
≤5960–69≥70 value

Surgical resection859 (39.6%)390 (28.9%)194 (18.0%)<0.001
Liver transplantation35 (1.6%)12 (0.9%)0 (0.0%)<0.001
Local ablative therapy422 (19.4%)289 (21.4%)200 (18.5%)0.784
Transarterial therapy729 (33.6%)553 (41.0%)518 (48.0%)<0.001
Systemic chemotherapy7 (0.3%)6 (0.4%)7 (0.6%)0.188
Radiation therapy7 (0.3%)12 (0.9%)4 (0.4%)0.525
No treatment112 (5.2%)88 (6.5%)157 (14.5%)<0.001

n = 4601Child–Pugh classification
ABC value
Surgical resection1390 (36.3%)52 (7.9%)1 (0.9%)<0.001
Liver transplantation24 (0.6%)10 (1.5%)13 (11.5%)<0.001
Local ablative therapy776 (20.2%)116 (17.7%)19 (16.8%)0.094
Transarterial therapy1405 (36.7%)356 (54.4%)39 (34.5%)<0.001
Systemic chemotherapy14 (0.4%)6 (0.9%)0 (0.0%)0.282
Radiation therapy13 (0.3%)10 (1.5%)0 (0.0%)0.010
No treatment211 (5.5%)105 (16.0%)41 (36.3%)<0 .001