Research Article

Therapeutic Decision Making in Hepatocellular Carcinoma According to Age and Child–Pugh Class: A Nationwide Cohort Analysis in South Korea

Table 3

Treatment pattern change by age and the Child–Pugh classification in PVT-positive patients.

Treatment n = 605Age (years)
≤5960–69≥70 value

Surgical resection16 (4.6%)5 (3.5%)1 (0.9%)0.081
Liver transplantation3 (0.9%)3 (2.1%)0 (0.0%)0.748
Local ablative therapy3 (0.9%)1 (0.7%)1 (0.9%)0.996
Transarterial therapy160 (45.6%)64 (44.4%)43 (39.1%)0.262
Systemic chemotherapy54 (15.4%)15 (10.4%)14 (12.7%)0.292
Radiation therapy12 (3.4%)6 (4.2%)0 (0.0%)0.137
No treatment103 (29.3%)50 (34.7%)51 (46.4%)0.001

n = 605Child–Pugh classification
ABC value
Surgical resection20 (6.3%)2 (0.9%)0 (0.0%)<0.001
Liver transplantation2 (0.6%)2 (0.9%)2 (3.8%)0.094
Local ablative therapy4 (1.3%)1 (0.4%)0 (0.0%)0.211
Transarterial therapy178 (56.0%)81 (34.5%)8 (15.4%)<0.001
Systemic chemotherapy46 (14.5%)34 (14.5%)3 (5.8%)0.235
Radiation therapy13 (4.1%)5 (2.1%)0 (0.0%)0.060
No treatment55 (17.3%)110 (46.8%)39 (75.0%)<0.001

PVT, portal vein tumor thrombosis.