Research Article

Efficacy and Safety of EUS-Guided Choledochoduodenostomy Using Electrocautery-Enhanced Lumen-Apposing Metal Stents (ECE-LAMS) in the Treatment of Biliary Obstruction: A Systematic Review and Meta-Analysis

Table 1

Characteristics of studies included in the meta-analysis.

Author (year)CountryDesignSettingTotal patient (n)Age, mean (SD or range)MaleEtiology (n)Reason for failed ERCP (n)Stent diameterCBD diameter (mm)Median follow-up (day)

Jacques et al. (2020), [26]FranceProspectiveMulticenter7075 (61–92)38Pancreatic cancer (54),
Cholangiocarcinoma (3),
Ampullary cancer (4),
Duodenal cancer (2),
Others (7)
Duodenal stenosis (31),
Tumoral involvement of papilla (15),
Cannulation failure (17),
Other (1)
6 mm (60),
8 mm (9),
10 mm (1)
17.7 ± 5153
Jacques et al. (2019), [27]FranceRetrospectiveMulticenter5278 (61–92)24Pancreatic cancer (43),
Cholangiocarcinoma (2),
Duodenal lymphoma (1),
Duodenal cancer (2),
Degenerated IPMN (2),
Peritoneal carcinomatosis (1),
Stones (1)
Duodenal stenosis (18),
Tumoral involvement of papilla (10),
Cannulation failure (14),
Prior duodenal stent (9),
Other (1)
6 mm (43),
8 mm (7),
15 mm (2)
17.2 (9–25)157
El Chafic et al. (2019), [25]USARetrospectiveMulti-center6768.8 ± 11.821Peri-ampullary cancer (56)
Metastatic cancer (11)
Duodenal stenosis (28),
Tumoral involvement of papilla (28),
Cannulation failure (9)
10 mm (67)17.6 ± 3.6119#
Tsuchiya et al. (2018), [28]AsiaProspectiveMulticenter1970.6 ± 13.912Pancreatic cancer (10),
Cholangiocarcinoma (2),
Ampullary cancer (1),
Duodenal cancer (1),
Metastatic cancer (4),
Sarcoma (1)
Duodenal stenosis (4),
Cannulation failure (15)
6 mm (10),
8 mm (9)
17.3 ± 5.5145
Anderloni et al. (2019), [23]ItalyRetrospectiveSingle-center4673.1 ± 12.624Pancreatic cancer (40),
Cholangiocarcinoma (1),
Ampullary cancer (2),
Duodenal cancer (3)
Duodenal stenosis (9),
Tumoral involvement of papilla (19),
Cannulation failure (12),
Prior duodenal stent (6)
6 mm (21),
8 mm (19),
10 mm (6)
17.26 ± 3.3483
Anderloni et al. (2018), [24]ItalyRetrospectiveSingle-center1669.9 ± 13.38NANA6 mm (9),
8 mm (4),
10 mm (3)
NA138.7

CBD, Common bile duct; IPMN, intraductal papillary mucinous neoplasm; ERCP, endoscopic retrograde cholangiopancreatography; NA, not available; #20 patients were lost follow-up.