LncRNA ELF3-AS1 is a Prognostic Biomarker and Correlated with Immune Infiltrates in Hepatocellular Carcinoma

Table 3

ELF3-AS1 expression was associated with clinical characteristics of HCC (logistic regression).

Characteristics	Total (N)	Odds ratio (OR)	value
T stage (T2 & T3 & T4 vs. T1)	371	2.030 (1.345–3.078)	<0.001
N stage (N1 vs. N0)	258	2.862 (0.361–58.271)	0.365
M stage (M1 vs. M0)	272	66845126.402 (0.000-NA)	0.994
Pathologic stage (Stage III & Stage IV vs. Stage I & Stage II)	350	1.412 (0.873–2.298)	0.161
Tumor status (with tumor vs. tumor free)	355	1.456 (0.955–2.224)	0.081
Gender (male vs. female)	374	0.539 (0.346–0.835)	0.006
Race (Asian and black or African American vs. white)	362	1.363 (0.902–2.064)	0.142
Age (>60 vs. ≤60)	373	0.781 (0.519–1.173)	0.234
Weight (>70 vs. ≤70)	346	0.771 (0.504–1.176)	0.228
Height (≥170 vs. < 170)	341	0.698 (0.452–1.076)	0.105
BMI (>25 vs. ≤25)	337	0.777 (0.506–1.192)	0.249
Residual tumor (R1 & R2 vs. R0)	345	5.548 (1.789–24.281)	0.008
Histologic grade (G3 & G4 vs. G1 & G2)	369	2.446 (1.587–3.802)	<0.001
Adjacent hepatic tissue inflammation (mild and severe vs. none)	237	1.953 (1.167–3.293)	0.011
AFP (ng/ml) (>400 vs. ≤400)	280	3.237 (1.793–6.060)	<0.001
Albumin (g/dl) (≥3.5 vs. <3.5)	300	1.045 (0.610–1.794)	0.874
Prothrombin time (>4 vs. ≤4)	297	0.935 (0.568–1.537)	0.790
Child-Pugh grade (B & C vs. A)	241	0.471 (0.174–1.163)	0.115
Fibrosis Ishak score (1/2 & 3/4 & 5/6 vs. 0)	215	1.233 (0.702–2.180)	0.467
Vascular invasion (yes vs. no)	318	1.687 (1.060–2.702)	0.028