Low Serum miR-607 Level as a Potential Diagnostic and Prognostic Biomarker in Patients of Pancreatic Ductal Adenocarcinoma: A Preliminary Study

Figure 1

The expression levels of miR-607 in patients with PDAC. (a) qRT-PCR analysis of miR-607 expression levels (normalized to U6) in 50 pairs of PDAC tumor tissues and adjacent normal tissues. (b) Analysis of serum miR-607 levels in 184 pairs of PDAC patients and healthy controls. (c) Comparison of the relative expression levels of miR-607 in PDAC tumor tissues with positive lymphatic metastasis and other PDAC tumor tissues with negative lymphatic metastasis. (d) The expression levels of miR-607 were analyzed in PDAC tumor tissues with positive perineural invasion and other PDAC tumor tissues with negative perineural invasion. (e) Levels of miR-607 in the BxPc-3 and PANC-1 cells are lower than those in the HPDE6c7 cells. qRT-PCR: quantitative real-time polymerase chain reaction, PDAC: pancreatic ductal adenocarcinoma. Data are represented as the mean ± SD from three independent experiments.

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