Low Serum miR-607 Level as a Potential Diagnostic and Prognostic Biomarker in Patients of Pancreatic Ductal Adenocarcinoma: A Preliminary Study

Table 3

Multivariate Cox regression analysis of different prognostic factors for OS in PDAC patients.

Features	Multivariate analysis
	RR	95% CI	Value
Age (≥60 years vs. < 60 years)	—	—	—
Gender (male vs. Female)	—	—	—
Tumor size (≥3 cm vs. < 3 cm)	—	—	—
Differentiation (poor vs. Well - moderate)	—	—	—
Clinical stage (III-IV vs. I-II)	2.136	0.932–3.510	0.064
T Stage (T3-T4 vs. T1-T2)	—	—	—
Lymphatic metastasis (positive vs. Negative)	1.472	0.733–2.659	0.218
Perineural invasion (positive vs. Negative)	1.755	0.619–3.021	0.077
Liver metastasis (positive vs. Negative)	1.246	0.402–2.115	0.430
CEA level (≥5 ng/mL vs. <5 ng/mL)	—	—	—
CA19-9 level (≥35 U/mL vs. <35 U/mL)	—	—	—
miR-607 level (high vs. low)	0.449	0.253–0.861	0.036