Predictors of Successful Yttrium-90 Radioembolization Bridging or Downstaging in Patients with Hepatocellular Carcinoma

Table 6

Penalized logistic regression analysis of the significant baseline characteristics.

Significant predictors	Favorable response
	β	Exp (β)
HCC diagnosis by biopsy	−0.402	0.669
Etiology of liver disease
Hepatitis B virus	−0.244	0.784
Other	−0.052	0.949
Lesion characteristics
Largest lesion diameter, in mm	−0.003	0.997
Total tumor cumulative diameter, in mm	−0.005	0.995
Presence of ≥4 viable HCC masses	−0.314	0.730
Affected hepatic lobe
Right lobe disease	−0.434	0.648
Left lobe disease	0.311	1.365
Multilobar disease	−0.398	0.671
ALBI grade
Grade 2	−0.094	0.911
Child–Pugh class
Class A	0.171	1.186
Class B	−0.171	0.843
BCLC stage
Stage A	0.320	1.377
Stage B	−0.382	0.682
Baseline symptoms
Fatigue	−0.032	0.969
Abdominal pain	−0.336	0.715
Nausea	0.215	1.240
Baseline laboratory levels
Albumin (g/dL)	0.293	1.340

β = regression coefficient; exp (β) = odds ratio. HCC = hepatocellular carcinoma; ALBI = albumin-bilirubin; BCLC = Barcelona Clinic Liver Cancer.