Reporting and Performance of Hepatocellular Carcinoma Risk Prediction Models: Based on TRIPOD Statement and Meta-Analysis

Table 1

The basic features of included studies.

	The first author	Year	Study interval	Region	Race	Setting	Model	Antiviral therapy	Sample size
1	Wong, G. L.	2013	2005.12–2012.8	China	Asian	Hospital	CU-HCC, GAG-HCC, and REACH-B	Entecavir	1531
2	Abu-Amara, Mahmoud	2016	—	Canada	Asian, Caucasian, and African	Hospital	CU-HCC, GAG-HCC, and REACH-B	Nucleotide analog, interferon	2105
3	Arends, P.	2015	2005–2013.5	European	Asian, Caucasian	Hospital	CU-HCC, GAG-HCC, and REACH-B	Entecavir	744
4	Lee, Hye Won	2019	2010–2016	Korea	Asian	Hospital	CU-HCC, GAG-HCC, PAGE-B, mPAGE-B, and REACH-B	Entecavir, tenofovir, and lamivudine	1330
5	Jeon, Mi Young	2018	2006–2014	Korea	Asian	Hospital	CU-HCC, REACH-B, and mREACH-B	No-classification	1397
6	Papatheodoridis, George V.	2015	—	Greece, Italy Spain, The Netherlands, and Turkey	Caucasian	Hospital	CU-HCC, GAG-HCC, and REACH-B	Entecavir, tenofovir,	1666
7	Kim, G. A.	2015	1997.1.1–2012.12.31	Korea	Asian	Hospital	CU-HCC	None	829
8	Kim, Ji Hyun	2018	2007.1–2016.6	Korea	Asian	Hospital	CU-HCC, GAG-HCC, PAGE-B, mPAGE-B, and REACH-B	Entecavir, tenofovir	1000
9	Brouwer, W. P.	2017	1985–2012	Rotterdam, The Netherlands	Asian, Caucasian, and African	Hospital	CU-HCC, GAG-HCC, PAGE-B, and REACH-B	No-classification	557
10	Yang, H. I.	2019	1997–2016	American, Asian-Pacific region	Asian American, and Asian	Hospital	CU-HCC, GAG-HCC, PAGE-B, and mPAGE-B, REACH-B	Oral antiviral	2683
11	Jeon, M. Y.	2017	2006.4–2014.12	Korea	Asian	Hospital	CU-HCC, REACH-B, and mREACH-B	No-classification	540
12	Tawada, Akinobu	2016	2000.11–2014.3	Japan	Asian	Hospital	CU-HCC, GAG-HCC	Entecavir, lamivudine	225
13	Jung, K. S.	2015	2006–2011	Korea	Asian	Hospital	CU-HCC, GAG-HCC, REACH-B, and mREACH-B	No-classification	1308
14	Kim, M. N.	2017	2006.8–-2015.1	Korea	Asian	Hospital	CU-HCC, GAG-HCC, PAGE-B, and REACH-B	Entecavir, tenofovir	1092
15	Riveiro-Barciela, M.	2017	2005.4–2015.09	Spain	Caucasian	Hospital	PAGE-B,	Emtricitabine, entecavir, tenofovir, and lamivudine	611
16	Seo, Yeon Seok	2017	2006–2012	Korea	Asian	Hospital	PAGE-B, REACH-B, and mREACH-B	—	1241
17	Magalhaes-Costa, Pedro	2016	2006.1–2014.2	Spain	Asian, Caucasian, and African	Hospital	REACH-B	Entecavir, tenofovir	120
18	Yang, H. I.	2016	—	China	Asian	Hospital	REACH-B	ERADICATE-B (none) CUHK (1/4)	ERADICATE-B (2688) CUHK(426)
19	Chen, T. M.	2013	2006.1–2012.5	China	Asian	Hospital	REACH-B	—	904
20	Chen, W.	2015	2004.10.1–2014.5.1	China	Asian	Hospital	REACH-B	—	627
21	Lee, H. W.	2014	2007.2–2011.1	Korea	Asian	Hospital	REACH-B	Entecavir	192
22	Yang, H. I.	2011	—	China,; Korea	Asian	Hospital	REACH-B	None	1505