Drug-Induced Liver Injury during Consolidation Therapy in Childhood Acute Lymphoblastic Leukemia as Assessed for Causality Using the Updated RUCAM

Table 7

Cases assessed as high causality of “probable” or “highly probable” in HR groups.

	No. of cases	HD-MTX	HD-Ara-C	PEG-ASP
HR-1	7	7 (100.0%)	4 (57.0%)	0 (0.0%)
HR-2	5	5 (100.0%)	NA	1 (20.0%)
HR-3	3	NA	3 (100.0%)	1 (33.3%)

HR, high risk; HD-MTX, high-dose methotrexate; HD-Ara-C, high-dose cytarabine; PEG-ASP, pegylated asparaginase; NA, not applicable.