Factors Prognostic of Survival in Liver Transplant Recipients with Hepatitis B Virus Related Acute-on-Chronic Liver Failure

Table 3

Univariate and multivariate Cox proportional hazards models of factors associated with post-LT survival in HBV-ACLF patients.

Characteristics	Reference	Hazard ratio^† (95.0% CI)	value	Hazard ratio^‡ (95.0% CI)	value
Recipient
Age >53 years	≤53	3.244 (1.564–6.730)	0.002	3.713 (1.640–8.407)	0.002
Serum urea >6.0 mmol/L	≤6.0	3.146 (1.517–6.525)	0.002	1.978 (0.900–4.439)	0.090
White blood cells >8.6 × 10^9/L	≤8.6	3.974 (1.839–8.589)	0.000	4.544 (1.140–18.107)	0.032
Neutrophils >6.6 × 10^9/L	≤6.6	3.069 (1.480–6.366)	0.003	0.722 (0.196–2.667)	0.625
HBV-ACLF 2	1	1.339 (0.527–3.401)	0.539	1.433 (0.531–3.871)	0.478
HBV-ACLF 3	1	3.496 (1.395–8.764)	0.008	2.729 (1.050–7.096)	0.039
Donor
HBsAg positive	Negative	2.850 (1.280–6.344)	0.010	2.328 (0.994–5.455)	0.052
Cold ischaemia time >8.5 hours	≤8.5	2.928 (1.464–5.855)	0.002	2.867 (1.389–5.921)	0.004

Notes: ^†Univariable analysis, ^‡Multivariable analysis.