MiR-766-3p Suppresses Malignant Behaviors and Stimulates Apoptosis of Colon Cancer Cells via Targeting TGFBI

Figure 3

MiR-766-3p inhibits TGFBI expression in colon cancer. (a) Volcano map of DEmRNAs in normal and tumor groups. (b) Venn diagram of DEmRNAs and predicted target mRNAs. (c) Correlation of miR-766-3p and TGFBI. (d) Box plot of the TGFBI level in normal and tumor groups. (e) Binding of miR-766-3p on TGFBI 3′UTR predicted by bioinformatics analysis. (f) Dual-luciferase assay measuring the luciferase activity in different treatment groups of the cancer cell line Caco-2. (g) TGFBI mRNA level in colon cancer cells Caco-2 upon miR-766-3p overexpression. (h) TGFBI protein level in colon cancer cells upon miR-766-3p overexpression. .

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