Geographic Distribution of HCV Genotypes and Efficacy of Direct-Acting Antivirals in Chronic HCV-Infected Patients in North and Northeast China: A Real-World Multicenter Study
Table 4
Clinical and virological characteristics of chronic hepatitis C patients with DAAs treatment.
Patients’ characteristics
n = 405
Female, n (%)
232 (57.14%)
Median age (IQR), years
56 (49, 63)
Median BMI (IQR), kg/m2
24.17 (21.97, 26.30)
Cirrhosis, n (%)
164 (40.39%)
Compensated
107 (26.35%)
Decompensated
57 (14.04%)
HCC, n (%)
12 (2.96%)
Comorbidity, n (%)
Hypertension
59 (14.53%)
Type 2 diabetes
71 (17.49%)
Hematological system disease
3 (0.74%)
Median baseline HCV RNA (IQR), lg·IU/ml
6.23 (5.52, 6.71)
Noncirrhosis
6.24 (5.52, 6.76)
Compensated cirrhosis
6.26 (5.53, 6.62)
Decompensated cirrhosis
5.86 (5.12, 6.49)
Genotypes, n (%)
1b
321 (79.06%)
2a
74 (18.23%)
3a
3 (0.74%)
3b
3 (0.74%)
6a
5 (1.23%)
Treatment history, n (%)
Naive
379 (93.35%)
Experience
27 (6.65%)
HCV: hepatitis C virus; DAA: directing antiviral agents; BMI: body mass index; HCC: hepatocellular carcinoma; and IQR: interquartile range.