Research Article

Geographic Distribution of HCV Genotypes and Efficacy of Direct-Acting Antivirals in Chronic HCV-Infected Patients in North and Northeast China: A Real-World Multicenter Study

Table 4

Clinical and virological characteristics of chronic hepatitis C patients with DAAs treatment.

Patients’ characteristicsn = 405

Female, n (%)232 (57.14%)
Median age (IQR), years56 (49, 63)
Median BMI (IQR), kg/m224.17 (21.97, 26.30)
Cirrhosis, n (%)164 (40.39%)
 Compensated107 (26.35%)
 Decompensated57 (14.04%)
HCC, n (%)12 (2.96%)
Comorbidity, n (%)
 Hypertension59 (14.53%)
 Type 2 diabetes71 (17.49%)
 Hematological system disease3 (0.74%)
Median baseline HCV RNA (IQR), lg·IU/ml6.23 (5.52, 6.71)
 Noncirrhosis6.24 (5.52, 6.76)
 Compensated cirrhosis6.26 (5.53, 6.62)
 Decompensated cirrhosis5.86 (5.12, 6.49)
Genotypes, n (%)
 1b321 (79.06%)
 2a74 (18.23%)
 3a3 (0.74%)
 3b3 (0.74%)
 6a5 (1.23%)
Treatment history, n (%)
 Naive379 (93.35%)
 Experience27 (6.65%)

HCV: hepatitis C virus; DAA: directing antiviral agents; BMI: body mass index; HCC: hepatocellular carcinoma; and IQR: interquartile range.