Research Article

Nomogram for Predicting Postoperative Portal Venous Systemic Thrombosis in Patients with Cirrhosis Undergoing Splenectomy and Esophagogastric Devascularization

Table 1

Characteristics of patients in the non-PVST and PVST groups.

FactorsNon-PVST(119)PVST(76) value

Preoperative
Age (years)48.90 (10.32)46.16 (9.26)0.061
BMI (kg/m2)22.60 (20.85, 24.40)22.80 (20.90, 24.52)0.81
Gender (%)Female44 (37.0)23 (30.3)0.419
Male75 (63.0)53 (69.7)
Diabetes (%)No107 (89.9)70 (92.1)0.794
Yes12 (10.1)6 (7.9)
Hypertension (%)NO114 (95.8)76 (100.0)0.178
Yes5 (4.2)0 (0.0)
Emergency (%)No108 (90.8)73 (96.1)0.266
Yes11 (9.2)3 (3.9)
Child-Pugh (%)A84 (70.6)58 (76.3)0.477
B35 (29.4)18 (23.7)
Ascites (%)No99 (83.2)59 (77.6)0.436
Yes20 (16.8)17 (22.4)
Bleeding history (%)No73 (61.3)31 (40.8)0.008
Yes46 (38.7)45 (59.2)
Cause of cirrhosis (%)Others29 (24.4)26 (34.2)0.185
HBV90 (75.6)50 (65.8)
The thickness of spleen (mm)56.00(50.50, 63.50)57.30 (53.00, 67.00)0.099
Length of spleen (mm)170.00(155.00, 183.50)186.00 (165.00, 203.75)<0.001
PVD (mm)12.80 (12.00, 13.50)14.75 (13.20, 16.85)<0.001
PVV (mm/s)17.20 (14.95, 20.10)18.40 (14.78, 20.19)0.27
MELD10.00 (9.00, 12.00)10.00 (9.00, 13.00)0.526
WBC (103/uL)2.18 (1.79, 2.90)1.94 (1.52, 2.66)0.023
RBC (106/uL)3.42 (0.63)3.48 (0.58)0.537
HB (g/L)101.97 (21.88)93.97 (20.91)0.012
Lymphocyte (103/uL)0.59 (0.46, 0.82)0.48 (0.36, 0.64)0.001
PLT (103/uL)38.00 (26.50, 52.50)36.50 (28.00, 53.00)0.713
Neutrocyte (103/uL)1.30 (0.98, 1.83)1.13 (0.86, 1.79)0.176
Monocyte (103/uL)0.20 (0.15, 0.28)0.17 (0.14, 0.29)0.274
PT (s)15.30 (13.80, 16.95)15.55 (14.57, 16.62)0.625
APTT (s)40.20 (34.15, 46.10)40.50 (35.03, 45.42)0.811
FIB (g/L)1.67 (1.33, 2.08)1.39 (1.20, 1.74)0.003
TT (s)18.30 (13.20, 21.20)19.50 (17.08, 21.08)0.087
HCT (%)29.90 (26.45, 33.90)27.95 (25.70, 31.15)0.013
MPV (fl)10.40 (9.55, 12.15)10.30 (9.70, 11.62)0.718
PDW (fl)17.30 (15.95, 17.86)17.16 (16.05, 18.25)0.608
RDW (%)15.60 (14.50, 17.35)17.15 (14.90, 20.30)0.002
Albumin(g/L)36.40 (33.40, 39.35)37.05 (34.18, 40.40)0.262
Globin (g/L)27.20 (22.65, 30.30)26.45 (22.45, 28.77)0.147
ALT (U/L)24.70 (17.25, 32.95)20.25 (16.05, 27.70)0.093
AST (U/L)29.60 (22.10, 37.45)24.10 (20.00, 32.47)0.011
TBIL (umol/L)20.80 (15.00, 30.15)20.60 (13.30, 27.42)0.436

Postoperative
RBC3.36 (0.58)3.53 (0.67)0.062
PLT76.00 (60.50, 97.50)83.00 (59.00, 100.00)0.708
RDW1 (%)15.40 (14.60, 17.05)16.90 (15.10, 19.65)0.004
RDW3 (%)15.40 (14.55, 17.00)18.65 (14.97, 21.30)<0.001
RDW7 (%)15.60 (14.40, 17.20)16.00 (14.78, 19.20)0.044
MPV1 (%)11.30 (10.24, 12.40)11.05 (10.30, 11.95)0.818
MPV3 (%)11.40 (10.07, 12.40)11.15 (10.40, 12.70)0.498
MPV7 (%)10.79 (1.36)10.94 (1.51)0.459
PDW1 (%)17.10 (16.18, 17.85)17.10 (16.28, 17.92)0.853
PDW3 (%)16.40 (15.93, 16.95)16.58 (15.87, 17.17)0.443
PDW7 (%)16.10 (15.38, 16.40)15.90 (14.40, 16.31)0.229

Bold indicates value < 0.05. BMI: body mass index, PVD: portal vein diameter, PVV: portal vein velocity, MELD: model for end-stage liver disease, TBIL: total bilirubin, WBCs: white blood cell, RBC: red blood cell, HB: hemoglobin, PT: prothrombin time, PLT: platelet, APTT: activated partial thromboplastin time, FIB: fibrinogen, TT: thrombin time, HCT: hematocrit, MPV: mean platelet volume, PDW: platelet distribution width, RDW: red blood cell distribution, AST: aspartate aminotransferase, and ALT: alanine aminotransferase.Numbers 1, 3, and 7 represent the factors on a postoperative day (POD) 1, 3, and 7, respectively.